Tīmeklis2007. gada 10. jūl. · Transcription repressor. Required for the specification of corticospinal motor neurons and other subcerebral projection neurons. May play a role in layer and neuronal subtype-specific patterning of subcortical projections and axonal fasciculation. Controls the development of dendritic arborization and spines of large … Tīmeklis2024. gada 22. jūn. · The zinc-finger transcription factor Fezf2 is expressed in deep-layer neurons. It promotes a subcerebral neuronal identity and suppresses …
Cell:增强大脑中Fezf2神经元的活动在一定程度上使小鼠工作得更 …
Tīmeklis2024. gada 20. febr. · 神经元单细胞亚群划分主要是靠转录因子 以上绝大部分研究都是根据释放的神经递质对转化的神经元亚型进行区分,特别是谷氨酸能和 GABA 能神经元,它们分别是大脑中主要的兴奋性和抑制性神经元。 大多数 Neurog2 或 NeuroD1 转换的神经元是前脑谷氨酸能神经元,而 Ascl1 显示出 GABA 能神经元生成的趋势。 不同 … Tīmeklis2008. gada 12. aug. · We and others have shown that a gene expressed specifically by subcortical projection neurons, Fezf2, is required for the formation of axonal … mobster movies on prime
Nature最新报道:锥体神经元亚型的多样性可控制新皮质中小胶质 …
Tīmeklis036296 B6;129S4- Fezf2 tm1.1(cre/ERT2)Zjh /J Fezf2-2A-CreER knock-in mice express tamoxifen-inducible CreERT2 fusion protein from the mouse Fezf2 (Fez family zinc finger 2) promoter in FEZF2-positive cortical … TīmeklisNasopharyngeal carcinoma (NPC) is an Epstein-Barr virus-associated tumor prevalent in southern China and southeast Asia, with the 3p14-p12 locus reported as a critical tumor suppressor gene (TSG) region during its pathogenesis. We identified a novel 3p14.2 TSG, FEZF2 (FEZ family zinc finger 2), for … Tīmeklis2013. gada 14. maijs · FEZF2 is readily expressed in normal tissues including upper respiratory epithelium, testis, brain and ovary tissues, as well as in immortalized nasopharyngeal epithelial cell line NP69, but it is completely silenced in NPC cell lines due to CpG methylation of its promoter, although no homozygous deletion of FEZF2 … mobster music