WebAnaemia can be the result of nutrient deficiencies, for example, iron, B12 or folate. Skin manifestations are: Pallor of the conjunctiva (eyes) and palmar creases. Glossitis (smooth red tongue) Poikilodermatous hypopigmentation. Hyperpigmentation may be a sign of B12 and folate deficiencies. WebOct 25, 2024 · Sickle cell disease (SCD) usually manifests early in childhood. For the first 6 months of life, infants are protected largely by elevated levels of Hb F; soon thereafter, the condition becomes evident. The most common clinical manifestation of SCD is vaso-occlusive crisis. A vaso-occlusive crisis occurs when the microcirculation is obstructed ...
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Sickle cell anemia - Diagnosis and treatment - Mayo Clinic
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