Solubility of benzocaine in water
WebBenzocaine is a water-insoluble ester-type local anesthetic agent that is mainly useful for topical application. The onset of action is rapid (<1 minute), and the effective duration is 5 … WebOct 4, 2005 · Benzocaine (BZC) is a local anesthetic whose low water-solubility limits its application to topical formulations. The present work focuses on the characterization of inclusion complexes of BZC in beta-cyclodextrin (beta-CD). Differential scanning calorimetry and electron microscopy gave evidences of the formation and the morphology of the …
Solubility of benzocaine in water
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WebApr 3, 2024 · Benzocaine is a colorless trapezial crystal. Its melting point is 92℃ (88-90℃), boiling point is 183-184°C (1.87kPa). 1g of this drug is soluble in about 2500ml water, 5ml …
WebQuestion: E PEC diagrams IV Homework Answered Benzocaine is insoluble in water at all temperatures, but does show a slight increase in solubility at higher temperatures. Which PEC diagram best represents the mixed (M) and unmixed (UM) state of benzocaine in water? c B А n UM E M E. Ep M UM UM M # of configurations # of configurations # of … WebJan 9, 2011 · Benzocaine is an effective general anesthetic for fish. Its solubility was determined in waters of various hardness and pH and over a range of temperatures (from 5 to 30°C). Variations in water hardness and pH did not appreciably affect the solubility of Benzocaine, whereas increases in temperature increased solubility from 409 mg/L (at 5°C …
WebJan 28, 2015 · The solute-free composition dependence of the log excess solubility of component 1 (the solute, ln x 1 , m E ) in the binary water(2)/ethanol(3) solvent, where component 1 is benzocaine or ... WebFeb 1, 2012 · Benzocaine Add to My Records Monograph ID: M2358. Title: Benzocaine Molecular Formula: C 9 H 11 NO 2. Molecular Weight: 165.19 Percent Composition: C 65.44%, H 6.71%, N 8.48%, O 19.37% ...
Benzocaine is the ethyl ester of p-aminobenzoic acid (PABA). It can be prepared from PABA and ethanol by Fischer esterification or via the reduction of ethyl p-nitrobenzoate. Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform, and ethyl ether. The melting point of benzocaine is 88–92 °C, and the boiling point is about 310 °C. The density of benzocaine is 1.17 g/cm .
WebWhat is the solubility of benzocaine in water? 0.4 g/L Benzocaine occurs in two forms: a crystalline salt (benzocaine HCl) that is soluble in water at 0.4 g/L, and a nonwater … onyx edition xtWebDec 1, 2002 · Benzocaine is sparingly soluble in water or an aqueous environment (solubility approx. 9.35 mmol/L at 37°C in aqueous media, with pH 7.4 and ionic strength 0.15 mol/L [16]), but its good ... iowa annuity suitability regulationsWebJun 30, 2024 · The equilibrium solubility of benzocaine (BZC) in several {methanol (1) + water (2)} mixtures at 298.15 K was determined. Solubility values are expressed in mole … onyx educate loginWebThe equilibrium solubility of benzocaine (BZC) in several {methanol (1) + water (2)} mixtures at 298.15 K was determined. Solubility values are expressed in mole fraction and molarity and were calculated with the Jouyban–Acree model. onyx edition outbackWebBenzocaine has limited solubility in water, but its conjugate acid is completely soluble in water. Draw the structure of the product formed from the reaction of benzocaine with hydrochloric acid. Click in the checkered box to open the structure drawing tool box. iowa annual conference centerWebFeb 2, 2024 · The present invention provides formulations of nanostructured gels for increased drug loading and adhesion. A wide range of drugs, particularly highly loaded with amine-containing compounds such as local anesthetics, which are known to be difficult to encapsulate (e.g., about 5% wt/wt drug/total gel weight and about 50% wt/wt drug/total … onyx effect tilesWebNov 15, 2004 · The solubility curves as a function of dioxane ratio showed a maximum at 90% dioxane at all temperatures. Above … The solubilities of benzocaine and salicylic acid were determined in water-dioxane mixtures at several temperatures (5-40 degrees C for benzocaine and 10-40 degrees C for salicylic acid). onyx effect porcelain tiles